PK/PD Analysis

An understanding of the relationship between drug concentration and clinical effect (beneficial and adverse) can aid decisions around the choice of a safe and effective dose.

Using our extensive experience, we can design, analyse, and report your pharmacokinetic studies so that they provide clarity on future drug development strategy.

We use industry standard software (Phoenix™ WinNonlin®) to aid our non-compartmental analysis and PK/PD modelling and simulation.

Our quality systems ensure the integrity of all our analyses and reports.

Enhancing your Decision-Making

Clients benefit from PharmaKinetic’s contributions in the following areas:

Safety Review

Interim PK and PD analysis and reporting for input into safety review meetings during dose escalation studies

Non-compartmental analysis

Non-compartmental analysis of PK and PD data from clinical pharmacology studies

Drug Concentration: Effect

PK/PD modelling of drug plasma concentration data against surrogate markers of efficacy in animals and humans

Dose Selection

Modelling and simulation to justify dose selection for pivotal clinical studies

Clinical Study Reports

Writing PK/PD sections for clinical study reports

Pre-clinical analysis

PK and TK data analysis and reporting for all your Discovery needs

Find Out More

Contact PharmaKinetic